A Non-Death Role of the Yeast Metacaspase: Yca1p Alters Cell Cycle Dynamics
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A Non-Death Role of the Yeast Metacaspase: Yca1p Alters Cell Cycle Dynamics
Caspase proteases are a conserved protein family predominantly known for engaging and executing apoptotic cell death. Nevertheless, in higher eukaryotes, caspases also influence a variety of cell behaviors including differentiation, proliferation and growth control. S. cerevisiae expresses a primordial caspase, yca1, and exhibits apoptosis-like death under certain stresses; however, the benefit...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2008
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0002956